Saturday, May 22, 2010

I'm just see-through, faded, super-jaded, out of my mind

So my psych has got me on Strattera, the norepinephrine reuptake inhibitor, again. For a month. If it doesn't work, she said the next course of action would be stimulants.

This comes as a relief.

That's an understatement.

Anyway, I'm on the Strattera right now--10 mg for the past five days, and tomorrow I go up to 18. Five days later I'll go up to 25, and then five days after that I'll go up to 40 for the remainder of the month. As I did last time I was on Strattera, I'm having a feeling of detachment, dissociation, disembodiment. Even on 10 mg. I feel like my body is...not quite mine. I look at my arms and they look far away. Sometimes everything in the room looks far away. I feel somewhat cut off from my emotions some of the time too. Which is not to say I cease having emotions, but they feel...I don't know, detached from me. I'm at a distance from them.

It's more weird than anything else. It doesn't upset me, thus far (when I went off the Strattera last time, it went away). I don't have a clue what's going to happen when my dose goes up, if even 10 mg can do this to me. Maybe I'll have an out-of-body experience? That would be fascinating.

Whatever the case may be, canoeing is over, so now I have...a week and a day of summer vacation before I go back to class until Thanksgiving break.

Edit: In doing some research, I found this:

"A high variety of factors have been implicated in the emergence of depersonalisation and derealisation episodes, including different drugs. A case abruptly induced by two applications of reboxetine, a selective and specific norepinephrine reuptake inhibitor, is reported occurring in a 50-year-old woman treated for a major depressive episode. The episode rapidly remitted after discontinuation of reboxetine. Previous data having indicated a role of the serotonin system in the pathophysiology of the phenomenon, a noradrenaline induced serotonin liberation of Raphe neurons is suggested as possible underlying mechanism."

(http://www.ncbi.nlm.nih.gov/pubmed/12947529)

So maybe this is something akin to that? I don't know. Depersonalization is reported as an occasional side effect of all of the meds that affect norepinephrine reuptake, as far as I can tell. Is this related? Will it become more related as my dose goes up? Who knows.